Incidence and factors associated with decreasing of glomerular filtration rate in patients with type 2 diabetes, King narai hospital

Abstract

Objectives of this study were: 1).To study the incidence of reduction of glomerular filtration rate in patients with type 2 diabetes, 2).To study the change in glomerular filtration level in patients with type 2 diabetes at duration of 6 and 12 month, and 3).To study the factors associated with the reduction of glomerular filtration rate in patients with type 2 diabetes from January to December 2020, total 360 patients. The tool used in the research was a data record of 2 parts, namely general data and laboratory results. Data were analyzed by descriptive statistics, T-test statistics and correlation coefficient.

             The results showed that of most of the 360 patients with ​​type 2 diabetes were 265 patients female (73.61%) with a mean age of 65.38 years (24-92 years) and an average BMI of 26.74 kg/m² (16-71 kg/m²). Most of them had multiple comorbidities such as hypertension (87.30%), followed by Dyslipidemia (47.71%). The decreasing of glomerular filtration rate was 49.72%. The stage 2 chronic kidney disease was the most (34.63%). The renal function had a statistically significant decrease at 6, 12 months (P≤0.05). When analyzing factors associated with reductions in glomerular filtration rate, age, duration of diabetes, Body mass index, BUN creatinine levels, and albumin urine is a factor associated with a decreasing the glomerular filtration rate with a statistically significant (P≤0.05).