The Trends of syphilis infection during pregnancy in a Tertiary Care Setting

Abstract

This Retrospective descriptive study aimed to determine the rate of syphilis infection in pregnancy, the incidence of congenital syphilis and factors associated to congenital syphilis among pregnancy who gave birth at Buddhachinaraj Hospital, Phitsanulok between January 1, 2015 - December 31, 2020. The study was conducted between April 2021 - March 2022. Among 177 samples, the data were analyzed using descriptive statistics such as frequency, percentage, mean (standard deviation), median (maximum-minimum) and inferential statistics such as Chi-square test and Multiple logistic statistics regression.

The results of a study showed that the syphilis infection rate among pregnancy in 2020 was the highest (2.46%), followed by 2019 (1.19%) and 2018 (0.76%) respectively.

The results of the multivariate polyregression analysis showed that birth weight was a statistically significant protective factor for congenital abnormalities (ORadj = 0.19, 95% CI = 0.0792 – 0.04603, p-value < 0.001.) and the treatment for maternal syphilis was a statistically significant protective factor for congenital abnormalities (ORadj = 0.18, 95% CI = 0.0669 – 0.05064, p-value = 0.001).

Should be defined guidelines for care and treatment of syphilis infection at all stages of pregnancy for prevention of syphilis infection in newborns and reduce stillbirth.