Risk factor for predict postoperative enterocolitis and anastomosis stricture in Hirschsprung’s Disease : A 5 years in Udonthani Hospital

Abstract

     This study aimed to explore and analyze the risk factors for postoperative complications in patients with Hirschsprung’s disease (HD).Two complication more interesting are Enterocolitis and anastomosis stricture. Retrospective cohort study in Patients with HD who treatment at Udonthani Hospital from 2015 to 2020. Follow-up data collected included constipation, fecal incontinence, anastomotic fistula, Hirschsprung’s-associated enterocolitis (HAEC), and readmission. The putative risk factors for postoperative complications in patients with HD were as follows: clinical classification,
gender, operative age, hemoglobin and serum albumin levels and preoperative HAEC. A follow-up survey was conducted for all patients by telephone. Data were analyzed statistically using SPSS version 23.0.

     Results: A total of 45 patients were included in the study.Male 37 patients and Female 8 patients. 7 patients had associated anomalies. 26 patients (57.7%) who had postoperative complications. Among patients with complications: 20 had post-operative HAEC(44.4%), 10 had anastomosis stricture(22.2%). Risk factor for Post-operative HAEC significant differences were Pre operative HAEC (pvalue 0.036) and Anastomosis stricture (Log rank test, p-value 0.03). Risk factor for anastomosis stricture significant differences were Post-operative HAEC (p-value 0.039) and Age of Surgery < 30 day (Log rank test, p-value 0.028)