Development of Hanumanprasankai Drug Formulations for Adjunctive Treatment of Asthma

Abstract

     The purpose of this article is to develop Hanumanprasankai drug in the form of a soluble infusion powder as an adjuvant in the treatment of asthma. It is an experimental research study by transforming the Hanumanprasankai drug in liquid form to powder form that contains maltodextrin in different proportions. Each proportion was compared in quantities, physical properties and chemical identities by Thin layer chromatography (TLC) determination. The study found that Hanumanprasankai drug in powder form with different proportions of maltodextrin, namely 20%, 40%, and 60%. Their different proportions of maltodextrin showed different colors according to the color bands, which are brown bands level 3, 2, and 1, respectively. Powder quantity before brewing had different weights: 10.39, 20.09, and 28.00 grams, respectively. The time to dissolve in water was also different to 4, 7, and 12 seconds, respectively and the specific gravity is also different to 0.008, 0.56 and 0.60, respectively. While the color after dissolving, the smell, the taste, and the acidity - base (pH) was not different. When determine the chemical identities using Thin layer chromatography (TLC), it was separated to 2 bands which the rate of flow (R_f) is 0.50 and 0.58, similar to Hanumanprasankai drug in liquid form. In conclusion, Hanumanprasankai powder with a maltodextrin ratio of 20% is mostly appropriate. This is because it uses the least amount of maltodextrin absorbent, the dissolution time is fastest with the least of specific gravity.