การรักษาผู้ป่วยโรคเริมด้วยครีมพญายอเทียบกับครีม Acyclovir ในโรงพยาบาลพระนั่งเกล้า

Nicha Jenmanachaiyakun

Authors

Nicha Jenmanachaiyakun -

Keywords:

Herpes simplex treatment, Payayor cream, Acyclovir cream, Alternative medicine

Abstract

The study was a randomized controlled trial in order to study the clinical outcomes on the treatment of herpes simplex patients using Payayor cream in Pranangklao hospital. Twenty-nine patients with herpes simplex labialis received treatment from dermatologists in Pranangklao hospital, Nonthaburi province, from January 2025 to June 2025, divided by a simple random sampling using the computer program into 2 groups. Group 1 received treatment for herpes simplex with Payayor cream, 15 cases. Group 2 received treatment for herpes simplex with Acyclovir cream, 14 cases. Comparison of mean satisfaction, pain score, itch score and treatment results of herpes simplex (3 stages of disease progression) by using statistical student t-test.

Results: Twenty-nine herpes simplex patients were compared with the mean satisfaction scores of the 9 items between the two groups. There was no statistically significant difference. The mean of satisfaction increased with the duration of treatment in the range of 2.47-4.80 in patients treated with Payayor cream and in the range of 2.36-4.64 in patients treated with Acyclovir cream. The treatment results in both groups were divided into 3 stages. Based on daily follow-up photographs assessed by dermatologists, there was no statistically significant difference between the two groups in 3 stages. The time to heal in patients treated with Payayor cream and Acyclovir cream were 8.87 ± 2.88 days and 9.71 ± 3.41 days, respectively (p = 0.48). There were no statistically significant differences in pain score and itch score between the two groups on day 3, 7 and 14.

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