อุบัติการณ์ของมะเร็งแฝงในผู้ป่วยที่มีภาวะหลอดเลือดดำส่วนลึกอุดตันโดยไม่ทราบสาเหตุ

Naruthep Nuchaikaew; Apiwat Wattanakul; Charinthorn Phaetyananthawet

Authors

Naruthep Nuchaikaew -
Apiwat Wattanakul -
Charinthorn Phaetyananthawet -

Keywords:

underlying malignancy, idiopathic deep vein thrombosis, incidence

Abstract

This retrospective cohort study aimed to determine the prevalence of latent malignancies in patients with a first diagnosis of unprovoked deep vein thrombosis (DVT). The study enrolled adult patients diagnosed with DVT and confirmed by imaging (e.g., ultrasound, Doppler, CT, or MRI) at Hat Yai Hospital between 2009 and 2019. Medical records were reviewed to assess the incidence of latent malignancies in patients with both provoked and unprovoked DVT.

Results: Between 2009 and 2019, a total of 1,770 patients were diagnosed with DVT, with 666 patients confirmed by imaging. Of these, 188 (28%) were unprovoked DVT patients. Twenty-eight patients, representing 14.8% of all unprovoked DVT patients, were later found to have underlying malignancies. Of these patients, 11 (40%) were male and 17 (60%) were female. Prostate cancer was the most common malignancy in males, accounting for 36% of the total. Gynecological malignancies were the most common in females, accounting for 41% of the total.

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