Incidence and factors associated with adverse reactions to blood transfusion at Ban Mi Hospital.
Keywords:
blood transfusion, adverse transfusion reactions, transfusion, incidenceAbstract
This study aimed to investigate the incidence, associated factors, and risk-reduction strategies for adverse transfusion reactions among patients at Ban Mi Hospital. A survey research by retrospective study was conducted by collecting data from patients who received blood and blood components between October 1, 2015, and September 30, 2024, totaling 12,572 patients. The study population consisted of 230 patients aged 15 years and older who experienced adverse transfusion reactions and had complete medical records. Data were analyzed using descriptive statistics, chi-square tests, and multiple logistic regression.
The results showed that the most common adverse reaction was chills (45.22%), followed by urticaria (39.13%). The blood component most frequently associated with adverse reactions was packed red cells (PRC), accounting for 70.00%. Most reactions occurred within 30 minutes to 1 hour after the initiation of transfusion. Factors significantly associated with adverse transfusion reactions included receiving more than three units of blood, a history of previous transfusions, a history of pregnancy, and a transfusion duration of less than three hours (p < 0.05).
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