ปัจจัยทำนายการกำเริบเฉียบพลันของโรคปอดอุดกั้นเรื้อรังในผู้ป่วยที่เข้ารับการรักษา โรงพยาบาลพนมสารคาม

Thatchapan  Ruangroj; Natthida  Jitpitayanupap; Duangmanee Wiyathus

Authors

Thatchapan Ruangroj -
Natthida Jitpitayanupap -
Duangmanee Wiyathus -

Keywords:

Chronic Obstructive Pulmonary Disease, Acute Exacerbation, Predictive Factors, Pneumonia, Drug Compliance

Abstract

This study aimed to investigate predictive factors associated with acute exacerbation in COPD patients managed at Phanomsarakham Hospital. Methodology This was Survey research by Retrospective Study conducted through a chart review of 255 COPD patients diagnosed before October 1, 2023, who had a history of treatment at the COPD clinic, inpatient wards, or the emergency room of Phanomsarakham Hospital between October 1, 2023, and September 30, 2024 (a 1-year period). The primary outcome was the occurrence of acute exacerbation requiring hospitalization or an emergency department visit during the 1-year follow-up. Predictive factors were analyzed using Multivariable Logistic Regression (Actual analysis required before publication).

Results Of the 255 patients, 72 (28.2%) experienced acute exacerbation. The analysis revealed that predictive factors significantly associated with acute exacerbation were: A history of acute exacerbation in the past year (Adjusted Odds Ratio, AOR = 4.31*, 95% CI: 2.15-8.62*, P = < 0.001*), A history of pneumonia in the past year (AOR = 3.85*, 95% CI: 1.51-9.82*, P = 0.005*), and Poor drug compliance (AOR = 5.25*, 95% CI: 1.05-26.25*, P = 0.043*).

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