Sex-Related Variations in Clinical Features and Prognosis of Stanford Type B Aortic Dissection: A Single-Center Retrospective Analysis
Keywords:
Type B aortic dissection, Sex differences, Treatment outcomes, Retrospective studyAbstract
The objective of this study was to examine the relationship between sex-based differences and clinical presentations, management strategies, and early outcomes among patients with Stanford Type B Aortic Dissection (TBAD). A retrospective descriptive study was conducted. The population comprised all consecutive patients admitted with confirmed TBAD at the Vascular Interventional Surgery Center of Workers' Hospital, Liuzhou, Guangxi, China, from January 1 to June 30, 2022. The sample consisted of 76 patients selected by purposive sampling. The research instrument was a medical record form developed in accordance with STROBE guidelines. Data collection was conducted through the hospital's electronic health information system together with ICD-10 codes. Data analysis utilized descriptive statistics, mean, standard deviation, median, interquartile range, t-test, Mann–Whitney U test, Chi-square test, Fisher's exact test, and Cox regression analysis.
The findings revealed that: 1) of the 76 patients, 16 (21.1%) were female and 60 (78.9%) were male; female patients demonstrated a significantly higher mean age at onset compared with males (68.3 ± 12.4 vs. 56.0 ± 12.6 years; P < 0.001); 2) hypertension was the most prevalent risk factor (92.1%); significant sex-based differences were observed for diabetes and heart failure (P < 0.050), and D-dimer levels differed significantly between sexes (P = 0.007); 3) endovascular procedures were performed in 53 patients (69.7%), with no significant sex-based variation in treatment allocation (P = 0.069); 4) the 30-day in-hospital mortality was 5.3%, showing no significant divergence between sexes (P = 0.193).
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